Inflammatory arthritis of Down's syndrome
By: Killeen, Orla.
Contributor(s): Foley, Charlene | Mac Dermott, Emma Jane | Wilson, Gerry | Fearon, Ursula | Veale, Douglas | Deely, Derek | Connolly, Joanna | Carroll, Deirdre.
Series: Down's Syndrome Association Journal 138 Autumn/Winter 2018: 27-28. 2018Content type: text Media type: unmediated Carrier type: volume Subject(s): DOWN SYNDROME
| INFLAMMATORY ARTHRITIS OF DOWN SYNDROME | PREVALENCE | RESEARCH | IRELAND | HEALTH INEQUALITIES | GPs LEARNING DISABILITY REGISTERSummary: Describes a national screening programme set up in Ireland in order to explore inflammatotr arthritis of Down's syndrome in terms of its clinical and radiological features, as well as to investigate the role of established biomarkers. This research, the largest of its kind to date, has shown that there is as increased risk of arthritis in children with T21, with a prevalence double that previously reported. Treatment is complicated by a high percentage of drug-associated complications. The investigators are now focusing on what might be driving the disease process by exploring three key areas: immunology, histology and genetics.
| Item type | Current library | Call number | Status | Date due | Barcode | Item holds | |
|---|---|---|---|---|---|---|---|
| Article Magazine | IHC Library | Article (Browse shelf(Opens below)) | Available (Article available on request) | W0010124 |
Describes a national screening programme set up in Ireland in order to explore inflammatotr arthritis of Down's syndrome in terms of its clinical and radiological features, as well as to investigate the role of established biomarkers. This research, the largest of its kind to date, has shown that there is as increased risk of arthritis in children with T21, with a prevalence double that previously reported. Treatment is complicated by a high percentage of drug-associated complications. The investigators are now focusing on what might be driving the disease process by exploring three key areas: immunology, histology and genetics.
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