Comorbid Down syndrome, Tourette syndrome and intellectual disability: registry prevalence and developmental course

By: Kerbeshian, J.
Contributor(s): Burd, L.
Series: Journal of Intellectual Disability Research 44 (1) 2000: 60-67.Publisher: 2000Content type: text Media type: unmediated Carrier type: volume Subject(s): DOWN SYNDROME | TOURETTE SYNDROME | COMORBID CONDITIONS | PREVALENCE | PROGNOSISSummary: The co-occurrence of Tourette Syndrome (TS) and Down's Syndrome (DS) has been previsouly reported in the literature. In the present study a retrospective record review was conducted using the North Dakota TS registery in order to ascertain the number of cases of TS and DS, and to develop case discriptions. We identified five cases from North Dakota. Two of these patients were simply comorbid for TS and DS. One was addittionally comorbid for bipolar disorder, another for childhood distintegrative disorder and a third had D/G group Translocation. The association between DS and TS occured in 2% of TS patients. Contrary to the situation in patients with pervasive developmental disorders, the presence of TS in DS may be a negative prognostic indicator. [AJ].
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The co-occurrence of Tourette Syndrome (TS) and Down's Syndrome (DS) has been previsouly reported in the literature. In the present study a retrospective record review was conducted using the North Dakota TS registery in order to ascertain the number of cases of TS and DS, and to develop case discriptions. We identified five cases from North Dakota. Two of these patients were simply comorbid for TS and DS. One was addittionally comorbid for bipolar disorder, another for childhood distintegrative disorder and a third had D/G group Translocation. The association between DS and TS occured in 2% of TS patients. Contrary to the situation in patients with pervasive developmental disorders, the presence of TS in DS may be a negative prognostic indicator. [AJ].

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