Drug treatment of depression associated with dementia or presented as 'Pseudodementia' in older adults with Down Syndrome

By: Tsiouris, John A.
Contributor(s): Patti, Paul J.
Series: Journal of Applied Research in Intellectual Disabilities 10 (4) 1997: 312-322. 1997Content type: text Media type: unmediated Carrier type: volume Subject(s): DOWN SYNDROME | DEPRESSION | DRUGS | SELECTIVE SEROTONIN RE-UPTAKE INHIBITOR (SSRI)Summary: Recommendations for treatment with antidepressants were followed in 10 cases with a marked improvement in functioning compared to a rapid decline in 10 cases where treatment was refused. Treatment with selective serotonin reuptake inhibitors antidepressant drugs resulted in improved quality of life, differentiated 'pseudodementia' from dementia, and possibly delayed the dementing process in adults with Down Syndrome and presentation of depression associated with dementia.
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Recommendations for treatment with antidepressants were followed in 10 cases with a marked improvement in functioning compared to a rapid decline in 10 cases where treatment was refused. Treatment with selective serotonin reuptake inhibitors antidepressant drugs resulted in improved quality of life, differentiated 'pseudodementia' from dementia, and possibly delayed the dementing process in adults with Down Syndrome and presentation of depression associated with dementia.

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