Differences in the clinical presentation of trisomy 21 with and without autism

By: Molloy, C A.
Contributor(s): Murray, D S | Kinsman, A | et al.
Series: Journal of Intellectual Disability Research 53 (2) 2009: 143-151.Publisher: 2009Content type: text Media type: unmediated Carrier type: volume Subject(s): DOWN SYNDROME | AUTISM | TRISOMY 21 | COMORBID CONDITIONSSummary: Notes that autism occurs ten times more often in children with Down syndrome than in the general population, but that diagnosing co-occurring autism in Down syndrome with severe mental disability is challenging. Presents a case-control study which aims to identify characteristics differentiating children with trisomy 21 with and without autism and to determine the extent to which severe cognitive impairment affects the measures of autism symptomatology.
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Notes that autism occurs ten times more often in children with Down syndrome than in the general population, but that diagnosing co-occurring autism in Down syndrome with severe mental disability is challenging. Presents a case-control study which aims to identify characteristics differentiating children with trisomy 21 with and without autism and to determine the extent to which severe cognitive impairment affects the measures of autism symptomatology.

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