A placebo double-blind pilot study of dextromethorphan for problematic behaviours in children with autism

By: Woodard, Cooper.
Contributor(s): Groden, June | Goodwin, Matthew | et al.
Series: Autism 11 (1) 2007: 29-41.Publisher: 2007Content type: text Media type: unmediated Carrier type: volume Subject(s): BEHAVIOUR PROBLEMS | CHILDREN | AUTISM | DRUG THERAPY | ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD)Summary: Uses a mixed group/single-case, double-blind placebo-controlled, ABAB design to examine the safety and efficacy of the glutamate antagonist dextromethorphan for the treatment of problematic behaviours and core symptoms in eight children diagnosed with autism. Finds that three of the eight participants who had a behavioural profile consistent with ADHD responded positively to dextromethorphan. Suggests further research is necessary.
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Uses a mixed group/single-case, double-blind placebo-controlled, ABAB design to examine the safety and efficacy of the glutamate antagonist dextromethorphan for the treatment of problematic behaviours and core symptoms in eight children diagnosed with autism. Finds that three of the eight participants who had a behavioural profile consistent with ADHD responded positively to dextromethorphan. Suggests further research is necessary.

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